Throughout 2011 Doctors Without Borders/Médecins Sans Frontières (MSF) ran medical projects in up to 22 different locations in south-central Somalia, the epicenter of the crisis, as well as large-scale programs in the Somali refugee camps in Ethiopia and Kenya. This document gives an overview of MSF activities related to the humanitarian crisis in Somalia and neighboring Kenya and Ethiopia. The data presented, though provisional, account for MSF’s medical activities and financial income and expenditures in this region, while the narrative illustrates how MSF as a medical aid organization responded to this evolving crisis.